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KMID : 0980720130320020178
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Keimyung Medical Journal
2013 Volume.32 No. 2 p.178 ~ p.182
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A Rare Case of Rathke Cleft Cyst with Xanthogranulomatous Change
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Kim Eal-Maan
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Abstract
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A rare case of symptomatic Rathke cleft cyst (RCC) with xanthogranulomatous change is reported, which is discovered in a 16-year-old girl presenting with primary amenorrhea and no development of secondary sexual characteristics. The endocrinological assessment revealed the patient had a hypogonadotropic hypogonadism. Brain magnetic resonance imaging demonstrated a 17 mm sized cystic lesion with rim enhancement in the intra- and suprasellar region. Via an endonasal microscopic approach, the cyst was completely decompressed and the cyst wall was partly excised. The cyst contents were confirmed intraoperatively with distinct colors and consistencies. Pathological examination of surgical specimen showed a nonciliated columnar epithelial lesion associated with xanthogranulomatous changes. The author speculate that xanthogranulomas in the sellar region might be caused by reaction to the presence of RCC.
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KEYWORD
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Amenorrhea, Hypogonadism, Rathke cleft cyst
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